clinical trial candidate +/- any molecular biomarker

your own Diagnostic lab at the touch of a button

KNOWN

Are you looking for candidates who are positive or negative for known CDx biomarkers
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    search lab network

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    pre-screened candidates

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    FDA-approved biomarkers

NOVEL

looking to bring a new CDx biomarker to the market and need to identify trial candidates
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    search genomic space

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    lab network

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    novel CDx biomarkers

SCREEN

can't find the candidates you need, we can screen for them using the assay of your choice
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    use our lab network

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    screen candidates

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    Dx assay of your choice

ARE YOU MISSING OUT?

Number of clinical trials with a mutational requirement is constantly increasing

Number of approved genomic biomarkers in oncology are rapidly increasing

FDA's CDx guidance is causing a flood of biomarkers to hit the market, the vast majority are detected by molecular tools such as PCR or NGS

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Oncology trials with genomic biomarker requirement are 10% and growing

FDA's CDx guidance requires all oncology therapies to have a molecular biomakers and CDx device to ensure the correct diagnosis is made

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Molecular pathology is not easy

how are you going to meet genomic eligibility requirements

More molecular biomarkers equals more molecular problems

The increase in CDx biomarkers is resulting in more complex diagnosis and staying on label is not easy. Below image shows the 7 approved biomarkers for EGFR and the approved diagnostic pathways to reach therapy.

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our scientists and engineers are regulatory experts

we've built and submitted regulated devices around the globe

EUROPE

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USA

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Software across the world

we know the clinical laboratory

users of karilian software solutions

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FIND+CONNECT

a patient::biomarker brokerage system

find patients who have the presence/absence of CDx molecular biomarker and route them to your treatments and clinical trials
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Core karilian technologies

how we surface molecular biomarker compliant candidates

1 Biomarker Positioning System

our data model knows the exact address of clinically revelant CDx biomarkers

2 Mapping System

we’ve created a map capturing all the streets connecting biomakers, CDx assays, drugs and clinical trials

3 Patient Routing System

we know how to find the path to your trial and route patients along it.

Known biomarkers

Find candidates who are positive or negative for known CDx biomarkers

Novel biomarkers

capture RWD as part of your trial and meet your RWE obligations

Reduce Screening Costs

remove CDx assays costs with pre-screened candidates

FIND+CONNECT

clinical trial candidate +/- any molecular biomarker

A diagnostic lab
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with zero infrastructure
Surface candidates
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without screening costs
Pay as you go
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for matching candidates